发明名称 HUMAN C-FMS ANTIGEN BINDING PROTEINS
摘要 Antigen binding proteins that bind to human c-fms protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of c-fms to CSF-1, reduce monocyte migration into tumors, and reduce the accumulation of tumor-associated macrophages.
申请公布号 US2009155164(A1) 申请公布日期 2009.06.18
申请号 US20080195169 申请日期 2008.08.20
申请人 AMGEN, INC. 发明人 BRASEL KENNETH ALLAN;SMOTHERS JAMES F.;CERRETTI DOUGLAS PAT;MEHLIN CHRISTOPHER;SUN JILIN;FOSTER STEPHEN
分类号 A61K38/00;A61K51/00;A61P29/00;A61P35/00;C07H21/04;C07K2/00;C07K16/18;C12N15/63;C12P21/00 主分类号 A61K38/00
代理机构 代理人
主权项
地址