TASTE MASKED CHEWABLE COMPOSITIONS OF SILDENAFIL CITRATE

摘要

The present invention relates to chewable solid pharmaceutical compositions comprising sildenafil citrate. Sildenafil citrate is a very bitter drug, hence the conventional tablets, comprise of a film coating for aesthetic appearance and acceptability. Chewable tablets are usually uncoated and hence there is a need to mask the bitter taste of sildenafil to ensure patient acceptability. The present invention achieves the taste masking of sildenafil citrate by using an ion-exchange resin which forms a complex and masks the bitter taste of sildenafil. The ion-exchange masked sildenafil complex is then incorporated with other excipients to formulate a chewable tablet using flavours and other ingredients.