发明名称 DIAGNOSIS AND PROGNOSIS OF BREAST CANCER PATIENTS
摘要 PROBLEM TO BE SOLVED: To provide genetic markers whose expression is correlated with breast cancer, specifically, sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. SOLUTION: The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein. COPYRIGHT: (C)2009,JPO&INPIT
申请公布号 JP2009131262(A) 申请公布日期 2009.06.18
申请号 JP20080319049 申请日期 2008.12.16
申请人 ROSETTA INPHARMATICS LLC;NETHERLANDS CANCER INST 发明人 DAI HONGYUE;HE YUDONG;LINSLEY PETER S;MAO MAO;ROBERTS CHRISTOPHER J;VAN'T VEER LAURA JOHANNA;VAN DE VIJVER MARC J;BERNARDS RENE;HART A A M
分类号 C12Q1/68;G01N33/53;C12M1/00;C12N15/09;C12Q1/02;C12Q1/04;G01N33/566;G01N33/574;G01N37/00;G06F19/20;G06F19/24 主分类号 C12Q1/68
代理机构 代理人
主权项
地址