发明名称 PEPTIDE SUBSTANCE REVEALING A STRESS PROTECTIVE EFFECT, PHARMACEUTICAL COMPOSITION ON ITS BASE, AND THE METHOD OF ITS APPLICATION
摘要 The invention is related to the medicinal means of prevention and treatment for functional or stress induced disorders, which occur as a result of extreme impacts, and may be used as a medication revealing a stress protective effect. There is proposed a peptide glutamyl-aspartyl-glycine with general formula H-Glu-Asp-Gly-OH sequence 1 [SEQ ID NO:1], revealing a stress protective effect. There is proposed a pharmaceutical composition revealing a stress protective effect, characterized in that such composition contains an effective amount of peptide glutamyl-aspartyl-glycine with general formula H-Glu-Asp-Gly-OH sequence 1 [SEQ ID NO:1] as its active base, as well as a pharmaceutically acceptable carrier. In this case such pharmaceutical composition exists in the form suitable for parenteral or intranasal administration. There is proposed a method of prevention and/or treatment for functional or stress induced disorders, which occur as a result of extreme impacts, such method consisting in the administration to a patient of a pharmaceutical composition containing an effective amount of peptide glutamyl-aspartyl-glycine with general formula H-Glu-Asp-Gly-OH sequence 1 [SEQ ID NO:1] as its active base in the dose of 0.01-100 mug/kg of body weight, at least once a day during a period necessary for attaining a therapeutic effect. In this case such administration is performed parenterally or intranasally.
申请公布号 US2009105158(A1) 申请公布日期 2009.04.23
申请号 US20070298430 申请日期 2007.03.05
申请人 OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTYU "SIA PEPTIDES" 发明人 KHAVINSON VLADIMIR KHATSKELEVICH;GRIGORIEV EVGENY IOSIFOVICH;MALININ VLADIMIR VICTORIVICH;RYZHAK GALINA ANATOLIEVNA
分类号 A61K38/06 主分类号 A61K38/06
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