发明名称 Thiophene and Thiazole Substituted Trifluoroethanone Derivatives as Histone Deacetylase (HDAC) Inhibitors
摘要 The present invention relates to compounds of formula (I), and pharmaceutically acceptable salts and tautomers thereof. Compounds of the present invention are inhibitors of histone deacetylase (HDAC) and are useful for treating cellular proliferative diseases, including cancer. They are also useful for treating neurodegenerative diseases, mental retardation, 10 schizophrenia, inflammatory diseases, restenosis, immune disorders, diabetes, cardiovascular disorders and asthma.
申请公布号 US2009076101(A1) 申请公布日期 2009.03.19
申请号 US20070223943 申请日期 2007.02.14
申请人 FERRIGNO FEDERICA;JONES PHILIP;MURAGLIA ESTER;ONTORIA ONTORIA JESUS MARIA;SCARPELLI RITA;SCHULTZ-FADEMRECHT CARSTEN 发明人 FERRIGNO FEDERICA;JONES PHILIP;MURAGLIA ESTER;ONTORIA ONTORIA JESUS MARIA;SCARPELLI RITA;SCHULTZ-FADEMRECHT CARSTEN
分类号 A61K31/426;A61K31/381;A61P3/00;A61P11/00;A61P25/00;A61P29/00;C07D277/20;C07D333/28 主分类号 A61K31/426
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