发明名称 |
Modified Adenovirus Hexon Protein and Uses Thereof |
摘要 |
The present invention provides a method of altering the specificity of an adenovirus vector. The method involves providing an adenovirus having a capsid with a modified adenovirus hexon protein. The modified adenovirus has a capsid comprising a hexon protein with a deletion in hypervariable region 1 and/or hypervariable region 4 of the hexon and an insert of an exogenous molecule therein.
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申请公布号 |
US2009074810(A1) |
申请公布日期 |
2009.03.19 |
申请号 |
US20070226593 |
申请日期 |
2007.04.27 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
ROY SOUMITRA;WILSON JAMES M. |
分类号 |
A61K39/00;A61K35/76;A61P31/00;C12N15/00 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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