HIGH-PRESSURE REFOLDING OF MONOCLONAL ANTIBODY AGGREGATES
摘要
<p>Methods for refolding antibodies, particularly monoclonal antibodies, from aggregated and/or denatured preparations by subjecting the antibody preparation to high hydrostatic pressure are provided. Refolded preparations of antibodies produced by the methods described herein are also provided.</p>
申请公布号
WO2009035617(A1)
申请公布日期
2009.03.19
申请号
WO2008US10595
申请日期
2008.09.10
申请人
BAROFOLD, INC.;SEEFELDT, MATTHEW, B.;RANDOLPH, THEODORE, W.;NELSON, ROBERT;HESTERBERG, LYNDAL, K.
发明人
SEEFELDT, MATTHEW, B.;RANDOLPH, THEODORE, W.;NELSON, ROBERT;HESTERBERG, LYNDAL, K.
