THE USE OF PYRIDONE DERIVATIVES FOR PREVENTING AND TREATING RADIATION INJURY OF LUNGS

摘要

The present invention is directed to a novel use of pyridone derivatives such as Pirfenidone for the treatment of radiation-induced lung injuries. Experiments indicated that pyridone derivatives can prevent radiation-induced lung injuries due to radiotherapy. Such prophylactic and/or therapeutic effects of the pyridone derivatives make it possible to increase therapeutic dosages of the radiotherapy, thereby enhancing the therapeutic efficacy of radiotherapy.