| 发明名称 |
C-GLYCOLIPIDS WITH ENHANCED TH-1 PROFILE |
| 摘要 |
The invention is directed to novel synthetic C-glycolipids that selectively induce a ThI-type immune response characterized by enhanced IL-12 secretion and increased activation of dendritic cells. The compounds of the invention are thereby useful in treating infections, cancers, cell proliferative disorders, and autoimmune diseases, both directly and as adjuvants. |
| 申请公布号 |
EP2035011(A2) |
申请公布日期 |
2009.03.18 |
| 申请号 |
EP20070762288 |
申请日期 |
2007.05.22 |
| 申请人 |
NEW YORK UNIVERSITY;THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OFNEW YORK;AARON DIAMOND AIDS RESEARCH CENTER |
发明人 |
TSUJI, MORIYA;CHEN, GUANGWU;FRANCK, RICHARD;YANG, GUANGLI |
| 分类号 |
C07D309/10;A61K31/70;C07H7/00 |
主分类号 |
C07D309/10 |
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