发明名称 |
METHOD FOR ANALYSIS OF POLYAMINES IN URINE OR PLASMA USING LIQUID CHROMATOGRAPHY/ELECTRONSPRAY IONIZATION-TANDEM MASS SPECTROMETRY ALONG WITH AMINE CARBAMYLATED DERIVATIZATION |
摘要 |
A method for detecting polyamine in urine or serum sample is provided to analyze it using sample of amount less than those of an existing method, to improve sensitivity of the analysis, to detect 9~10 kind of polyamines including cetyl polyamine at the same time and to decrease time, cost and effort required for analysis. A method for detecting polyamine in urine or serum sample includes steps of: derivatizing a polyamine within the urine or the serum sample into amine carbamylated and extracting selectively polyamine from the urine or the serum sample; separating the extracted polyamine using a high performance liquid chromatography(HPLC); and determining concentration of the polyamine by analyzing the separated polyamine by a mass spectrograph.
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申请公布号 |
KR20090027896(A) |
申请公布日期 |
2009.03.18 |
申请号 |
KR20070093075 |
申请日期 |
2007.09.13 |
申请人 |
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY |
发明人 |
BYUN, JEONG AH;CHUNG, BONG CHUL;JUNG, BYUNG HWA;LEE, JEONG AE |
分类号 |
G01N33/487;G01N30/02;G01N33/49;G01N33/493 |
主分类号 |
G01N33/487 |
代理机构 |
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