摘要 |
<p>Provided herein are compositions, combinations, and methods comprising NMDA antagonists including, but not limited to, NMDA glutamate receptor antagonists such as [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1-(7)-en-2-yl)alkyl]phosphonic acid and derivatives thereof, which are effective in reducing the amount of anesthetic required to maintain anesthesia (i.e. to achieve an anesthetic-sparing effect).</p> |
申请人 |
WYETH;EPPLER, CECIL, MARK;MUIR, WILLIAM, W., III;HUSTEAD, DAVID, ROBERT;CULLEN, THOMAS, GERARD;ZWIJNENBERG, RAPHAEL, JOHANNES, GERHARDUS |
发明人 |
EPPLER, CECIL, MARK;MUIR, WILLIAM, W., III;HUSTEAD, DAVID, ROBERT;CULLEN, THOMAS, GERARD;ZWIJNENBERG, RAPHAEL, JOHANNES, GERHARDUS |