发明名称 |
HETEROCYCLIC AMIDES USEFUL FOR THE TREATMENT OF CANCER AND PSORIASIS |
摘要 |
The present disclosure relates to heterocyclic amide compounds, which are useful for inhibiting the Hedgehog pathway, and their use in treating a disease or medical condition mediated alone or in part by Hedgehog pathway inhibition. Also disclosed are methods for manufacture of these compounds, pharmaceutical compositions including these compounds, and use of these compounds in the manufacture of medicaments for treating such diseases and medical conditions in a subject. Formula (IA) with the provisio that either R2or R3 is (Z).
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申请公布号 |
CA2696767(A1) |
申请公布日期 |
2009.03.05 |
申请号 |
CA20082696767 |
申请日期 |
2008.08.29 |
申请人 |
ASTRAZENECA AB |
发明人 |
DAKIN, LESLIE;FAUBER, BENJAMIN;HIRD, ALEXANDER;JANETKA, JAMES;RUSSELL, DANIEL JOHN;SU, QIBIN;YANG, BIN;ZHENG, XIAOLAN |
分类号 |
C07D213/30;A61K31/40;A61K31/41;A61K31/435;A61K31/4427;A61P35/00;C07D213/40;C07D213/73;C07D233/61;C07D401/12;C07D413/12;C07D417/12;C07D417/14;C07D473/00;C07D513/04 |
主分类号 |
C07D213/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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