发明名称 NOVEL PYRIMIDINE COMPOUNDS HAVING BENZYL (HETEROCYCLIC METHYL) AMINE STRUCTURE AND MEDICAMENT COMPRISING THE SAME
摘要 A compound represented by the following general formula (I), wherein R1, R2, R3, R4 and R5 represent hydrogen atom, a halogen atom, a lower alkyl group and the like, R6 represents an alkyl group, a cycloalkyl group and the like, R7 and R8 represent hydrogen atom, a lower alkyl group, a (lower cycloalkyl)(lower alkyl) group and the like, R9 represents hydrogen atom, a halogen atom, a lower alkoxy group and the like, R10 and R11 represent hydrogen atom, a lower alkyl group, a lower alkoxy group, a halo(lower alkyl) group and the like, and A represents a heterocyclic ring constituted by 6 to 10 atoms, which has potent inhibitory activity on cholesterol ester transfer protein (CETP).
申请公布号 US2009062306(A1) 申请公布日期 2009.03.05
申请号 US20080045982 申请日期 2008.03.11
申请人 KOWA COMPANY, LTD. 发明人 OHGIYA TADAAKI;MIURA TORU;OKUDA AYUMU;ARAI TOSHIHARU;YAMAZAKI KOICHI;AOKI TARO;MIYOSAWA KATSUTOSHI;SHIBATA HARUKI;SHIBUYA KIMIYUKI
分类号 A61K31/506;C07D401/12;C07D403/12 主分类号 A61K31/506
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