发明名称 |
METHOD FOR PRODUCING A THREE-DIMENSIONAL MACROPOROUS FILAMENT CONSTRUCT BASED ON PHASE INVERSION AND CONSTRUCT THEREBY OBTAINED |
摘要 |
The present invention relates to a method for producing a three-dimensional macroporous filament construct comprising interconnected microporous filaments showing a suitable surface roughness and microporosity. The method comprises the steps of: a) preparing a suspension comprising particles of a predetermined material, a liquid solvent, one or more binders and optionally one or more dispersants, b) depositing said suspension in the form of filaments in a predetermined three- dimensional pattern, preferably in a non-solvent environment, thereby creating a three-dimensional filament-based porous structure, c) inducing phase inversion, whereby said filaments are transformed from a liquid to a solid state, by exposing said filaments during the deposition of the filaments with a non-solvent vapour and to a liquid non-solvent, d) thermally treating the structure of step d) by calcining and sintering said structure. The invention further provides a three-dimensional macroporous filament construct comprising interconnected microporous filaments showing a specific surface roughness and microporosity. The invention also relates to various uses of the construct, including its use for the manufacture of a biomedical product, such as a synthetic bone implant or bone graft. |
申请公布号 |
WO2009027525(A2) |
申请公布日期 |
2009.03.05 |
申请号 |
WO2008EP61429 |
申请日期 |
2008.08.29 |
申请人 |
VITO NV;MULLENS, STEVEN HANS RIK WOUTER;THIJS, IVO;LUYTEN, JAN ROGER;BOUWEN, WIM LOUIS |
发明人 |
MULLENS, STEVEN HANS RIK WOUTER;THIJS, IVO;LUYTEN, JAN ROGER;BOUWEN, WIM LOUIS |
分类号 |
B22F3/22;B22F7/00;C04B35/63 |
主分类号 |
B22F3/22 |
代理机构 |
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