<p>The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.</p>
申请公布号
EP2029627(A2)
申请公布日期
2009.03.04
申请号
EP20070795607
申请日期
2007.06.01
申请人
AVEO PHARMACEUTICALS, INC.
发明人
HAN, MAY;WRIGHT, S. KIRK;WINSTON, WILLIAM M., JR.;BREAULT, LYNE;LIN, JIE;ETEMAD-GILBERTSON, BIJAN;KNUEHL, CHRISTINE;GYURIS, JENO