发明名称 |
Compounds for the Treatment of Neurodegeneration and Stroke |
摘要 |
Compounds and related methods for synthesis, and the use of compounds for the treatment of neurodegenerative diseases are disclosed. Compounds are disclosed in connection with PARG and/or PARP inhibition. Therapeutic applications are relevant for preventing or inhibiting neurological cell death for a variety of neurodegenerative conditions including Parkinson's disease, ischemia, and stroke. Also disclosed is a high-throughput screen for identifying compounds capable of inhibiting PARG and/or PARP.
|
申请公布号 |
US2009012088(A1) |
申请公布日期 |
2009.01.08 |
申请号 |
US20080129047 |
申请日期 |
2008.05.29 |
申请人 |
HERGENROTHER PAUL J;PUTT KARSON S;LIU XIANJUN |
发明人 |
HERGENROTHER PAUL J.;PUTT KARSON S.;LIU XIANJUN |
分类号 |
A61K31/5377;A61K31/50;A61K31/501;A61P25/00 |
主分类号 |
A61K31/5377 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|