HYDROGEL MATERIALS

摘要

The present invention relates to biocompatible crosslinked biomate rials made from polycondensation polymerization reactions involving polynucleophilic- polyelectrophilic precursors that address the limitations of steric hindrance, viscosity, and diffusion currently reducing gelation rates and curing thoroughness of the biomaterials. A cross-linking scheme is utilized in the invention that permits rapid gelation and thorough curing of the biomaterial. The biomaterial is made by polycondensation polymerization of polynucleophilic-polyelectrophilic precursors to form a water-soluble polymer crosslinked with a water-soluble crosslinker having at most one core cyclic structure.