POROUS COMPOSITE MATERIAL, PREPARATION PROCESS THEREOF AND USE TO REALIZE TISSUE ENGINEERING DEVICES

摘要

The present invention refers to a porous composite material, wherein at least one interdispersed biopolymer is present, with a calcium-phosphate mineral component comprising from 50 w/% to 95 w/% of a-tricalcium phosphate (a-TCP, a-Ca3 (PO4) 2) and from 5 w/% to 50 w/% of octacalcium phosphate (OCP, Ca8H2(PO4)6-5H2O), to the total weight of the mineral component. Such combination of a-TCP and OCP allows an in vivo faster resorption rate and thereby a faster formation of new bone tissue having a low cristallinity mineral component with nanocrystal structure, features very similar to those of biological apatites. This porous composite material may find application as bone and/or osteal- chart ilagineous substitute (scaffold) and in producing tissue engineering devices.