METHOD FOR THE GENERATION OF A NON-HUMAN ANIMAL WITH AN ONCOGENE

摘要

The present invention relates to a method for the generation of a non-human animal with random activation of several oncogenes, comprising - transfection of an animal or animal cell, preferably a stem cell, with one or more DNA constructs with at least two randomly inducible oncogenes and - the random induction of one or more of several inactive oncogenes in the animals or animal cells and - identifying and distinguishing one of the animals or animal cells with one randomly activated oncogene or an activated group of oncogenes from the other randomly generated animals or animal cells with different activated oncogenes.