摘要 |
<p>Compounds having the structure of Formula I1 including pharmaceutically acceptable salts of the compounds, are potent CETP (cholesterol ester transfer protein) inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis Atherosclerosis and its clinical consequences, coronary heart disease (CHD), stroke and penpheral vascular disease, represent a truly enormous burden to the health care systems ofthe industrialized world In formula I, A-B is an arylamide moiety</p> |
申请人 |
MERCK & CO., INC.;HUNT, JULIANNE, A.;SWEIS, RAMZI, F.;KIM, DOOSEOP;KALLASHI, FLORIDA;SINCLAIR, PETER, J. |
发明人 |
HUNT, JULIANNE, A.;SWEIS, RAMZI, F.;KIM, DOOSEOP;KALLASHI, FLORIDA;SINCLAIR, PETER, J. |