USE OF INHIBITORS OF SIRTUINS AND/OR AMPK FOR THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF POLYALANINE DISEASES.

摘要

This invention relates to the use of inhibitors of sirtuins and/or AMPK for the preparation of a medicament for the treatment of polyalanine diseases, in particular oculopharyngeal musculardystrophy (OPMD). The invention also relates to methods of identifying compounds which can be useful for treating said diseases.