THE METHOD OF DIAGNOSIS USING DOSAGE SENSITIVE GENE GROUP AND METHYLATION DEGREE OF METHYL TRANSITION ZONE THEREOF
摘要
<p>A cancer diagnosis method using a dosage sensitive gene group and the methylation degree of methyl transition zone thereof is provided to measure the existence and nonexistence of cancer, progress, and carcinogenesis reseaon. A cancer diagnosis method using a dosage sensitive gene group and the methylation degree of methyl transition zone thereof is characterized in that the CpG island is deficient; L1 factor is abundant; the value of the BOE (breadth of expression) is low; and the value of the PHE (peak height of expression) is high.</p>
申请公布号
KR20080111881(A)
申请公布日期
2008.12.24
申请号
KR20070060392
申请日期
2007.06.20
申请人
ORIENTBIO CO., LTD.;CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATIONFOUNDATION
发明人
RHYU, MUN GAN;HONG, SEUNG JIN;JUNG, YU CHAE;KIM, SANG NYUN;CHANG, JAE JIN;CHOI, SUK JONG