发明名称 TRICYCLIC INHIBITORS OF HYDROXYSTEROID DEHYDROGENASES
摘要 The present invention provides tricyclic compounds according to formula (I): (I) where R1, R2, R3, W, X, Y, Z, m, n, and p are as defined in the description; as well as pharmaceutical compositions comprising the same, methods of use of the compounds and compositions of the invention for the treatment of conditions associated with hydroxysteroid dehydrogenases (e.g., 11 -HSD1), and the use of the compounds of the invention in the preparation of medicaments for the treatment of hydroxysteroid dehydrogenase-associated conditions.
申请公布号 CA2691309(A1) 申请公布日期 2008.12.24
申请号 CA20082691309 申请日期 2008.06.11
申请人 AMGEN INC. 发明人 POWERS, JAY P.;SUN, DAQING;YAN, XUELEI;JULIAN, LISA;GONZALEZ LOPEZ DE TURISO, FELIX
分类号 C07D231/10;A61K31/41;A61P3/10;C07D261/06;C07D263/30;C07D277/20 主分类号 C07D231/10
代理机构 代理人
主权项
地址