The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with pathogens and vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interactions with the immune system.
申请公布号
EP2004808(A2)
申请公布日期
2008.12.24
申请号
EP20070753179
申请日期
2007.03.14
申请人
VAXDESIGN CORPORATION
发明人
WARREN, WILLIAM, L.;SANCHEZ-SCHMITZ, GUZMAN;HIGBEE, RUSSELL;FAHLENKAMP, HEATHER;DRAKE, DONALD, III;TEW, JOHN, G.