摘要 |
Disclosed is a compound useful as an inhibitor of 11²-hydroxysteroid dehydrogenase type 1.
A compound represented by the formula:
a pharmaceutically acceptable salt or solvate thereof,
wherein
R 1 is a group of the formula: -C(=O)NR 4 R 5 ,
(wherein R 4 and R 5 are each independently, hydrogen, optionally substituted alkyl or the like) or
a group of the formula: -NR 6 C(=O)R 7 ,
(wherein R 6 and R 7 are each independently, hydrogen, optionally substituted alkyl or the like),
X and Y are each independently -0- or the like,
Z is a bond or the like,
R 2 is optionally substituted alkyl, optionally substituted alkenyl or the like,
R 3 is optionally substituted alkyl, optionally substituted alkenyl or the like.
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