USE OF HIGH-DOSE OXAZAPHOSPHORINE DRUGS IN COMBINATION WITH MONOCLONAL ANTIBODIES FOR TREATING IMMUNE DISORDERS
摘要
<p>The present invention relates to methods of treating an autoimmune disorder, using a lymphocytotoxic but hematopoeitic cell sparing high-dose pulsed amount of an oxazaphosphorine drug in combination with immune therapeutics such as, for example, monoclonal antibodies that selectively bind B-cell specific antigens.</p>
申请公布号
WO2008156494(A1)
申请公布日期
2008.12.24
申请号
WO2007US81614
申请日期
2007.10.17
申请人
THE JOHNS HOPKINS UNIVERSITY;ACCENTIA BIOPHARMACEUTICALS, INC.;BRODSKY, ROBERT;JONES, RICHARD, J.;O'DONNELL, FRANK;BONITZ, SUSAN;SANTOS, CARLOS
发明人
BRODSKY, ROBERT;JONES, RICHARD, J.;O'DONNELL, FRANK;BONITZ, SUSAN;SANTOS, CARLOS
