PARALLEL FLOW CONTROL (PFC) APPROACH FOR ACTIVE CONTROL, CHARACTERIZATION, AND MANIPULATION OF NANOFLUIDICS

摘要

A method of active nanofluidic flow control (parallel flow control-PFC) includes providing a nanofluidic channel and a pressure-driven microfluidic channel connected in parallel and actively controlling flow through the nanofluidic channel by using the pressure-driven microfluidic channel. A method of nanofluidic flow measurement includes providing a nanofluidic channel, a pressure-driven microfluidic channel connected in parallel for flow control, and an additional measurement microfluidic channel connected in series for flow measurement and measuring the nanofluidic flow rate by measuring the filling rate in the measurement microfluidic channel. A method of nano-scale volume fluid manipulation includes providing a nanofluidic channel and a pressure-driven microfluidic channel connected in parallel and manipulating nano-scale volume fluid through the nanofluidic channel by using the pressure-driven microfluidic channel. A method of fabricating a fluidic system is provided. The method includes forming a nanofluidic channel and a pressure-driven microfluidic channel connected to the nanofluidic channel in parallel.