发明名称 Methods of treatement using CTLA-4 antibodies
摘要 The present invention provides method of treatment using human sequence antibodies against human CTLA-4 linked to a cytotoxic agent. In particular, methods of treating cancer and autoimmune disease are provided.
申请公布号 AU2003234736(B2) 申请公布日期 2008.09.25
申请号 AU20030234736 申请日期 2003.04.11
申请人 MEDAREX, INC. 发明人 ROBERT GRAZIANO;THOMAS DAVIS;TIBOR KELER;ALAN J KORMAN
分类号 A61K39/39;A61K;A61K38/00;A61K38/16;A61K39/00;A61K39/02;A61K39/12;A61K39/29;A61K39/395;A61P1/16;A61P11/06;A61P15/16;A61P19/02;A61P25/28;A61P29/00;A61P31/00;A61P31/04;A61P31/12;A61P31/14;A61P31/16;A61P31/18;A61P31/20;A61P31/22;A61P33/00;A61P33/02;A61P33/06;A61P35/00;A61P37/02;A61P37/04;A61P39/00;A61P43/00;C07K;C07K14/705;C07K16/28;C07K16/30 主分类号 A61K39/39
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