发明名称 |
CINNAMIC ACID, VANILLIC ACID AND BENZOFURAN DERIVATIVES FOR USE IN THE TREATMENT OF INFLAMMATION AND CANCER |
摘要 |
Novel compounds, their methods of preparation and use in therapies related to cancer and inflammation are provided. Compounds comprise esters of cinnamic acid, vanillic acid and 4- hyrdoxy cinnamic acid and derivatives and salts thereof. Compounds with novel benzofuran lignan structure as a potent antimitotic agent and inducer of apoptosis are provided. Formulations and methods for treatment of diseases mediated by NF-kappaB are also provided. |
申请公布号 |
WO2008062466(A3) |
申请公布日期 |
2008.09.25 |
申请号 |
WO2007IN00488 |
申请日期 |
2007.10.12 |
申请人 |
RELIANCE LIFE SCIENCES PVT. LTD. |
发明人 |
BOSE, JULIE, SAHA;GANGAN, VIJAY |
分类号 |
A61K31/216;A61K31/235;A61K31/343;A61K31/621;A61P29/00;A61P35/00 |
主分类号 |
A61K31/216 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|