发明名称 |
Cobalamin taxane bioconjugates |
摘要 |
The present invention is directed to methods and compositions including a taxane covalently bonded to the cobalt atom of a cobalamin. The composition can be delivered by any effective route, but is particularly useful as an oral anti-cancer or antiangiogenic compound. The anti-cancer/anti-angiogenic compound can be used in various chemotherapies including anti-angiogenic chemotherapies, alone or in combination with other anti-cancer/anti-angiogenic compounds.
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申请公布号 |
US2008233135(A1) |
申请公布日期 |
2008.09.25 |
申请号 |
US20080077060 |
申请日期 |
2008.03.14 |
申请人 |
GEBHARD JOHN R;VOLLMER DAVID;DAUGHERTY CLAIRE;PATEL DINESH |
发明人 |
GEBHARD JOHN R.;VOLLMER DAVID;DAUGHERTY CLAIRE;PATEL DINESH |
分类号 |
A61K47/48;A61K31/714;A61P35/00;C07H23/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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