发明名称 |
Piperidine Derivatives as Gcs Inhibitors |
摘要 |
The present invention relates to novel piperidine derivatives that are useful as inhibitors of glucosylceramide synthase (GCS) for use in the treatment and prevention of diseases or disorders mediated by GCS, including cancer, infectious diseases, neuronal disorders or injury and inflammatory diseases. The invention further relates to the pharmaceutical composition comprising the novel piperidine derivatives and methods for preparing the same.
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申请公布号 |
US2008234324(A1) |
申请公布日期 |
2008.09.25 |
申请号 |
US20050586188 |
申请日期 |
2005.01.11 |
申请人 |
ORCHARD MICHAEL GLEN;SCOPES DAVID IAN CARTER |
发明人 |
ORCHARD MICHAEL GLEN;SCOPES DAVID IAN CARTER |
分类号 |
A61K31/451;A61P3/04;A61P29/00;A61P35/00;C07D211/44;C07D211/46 |
主分类号 |
A61K31/451 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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