Microemulsion & sub-micron emulsion process & compositions

摘要

There is provided an oil in water microemulsion or sub-micron emulsion composition for dermal delivery of at least one pharmaceutically active ingredient, the composition comprising: an oil phase dispersed throughout a water phase, said oil phase including at least one of the group consisting of animal, mineral or vegetable oils, silanes, siloxanes, esters, fatty acids, fats, halogen compounds and alkoxylated alcohols, and at least one lipophilic surfactant; and said water phase including at least one hydrophilic surfactant, water and a non-surfactant amphphilic compound; wherein the weight ratio of the at least one hydrophilic surfactant to the at least one lipophilic surfactant is approximately 9.0:1.0 to 2.0:3Ø