发明名称 |
Synthesis of Polyanhydrides |
摘要 |
The present invention provides a method for forming compounds of Formula <?in-line-formulae description="In-line Formulae" end="lead"?>HO-C(-O)R<SUP>1</SUP>-X-R<SUP>2</SUP>-X-R<SUP>1</SUP>-C(-O)-O-H<?in-line-formulae description="In-line Formulae" end="tail"?> wherein compound (I) can be polymerized to provide a polymer that contains therapeutically active compounds. In the compounds of the invention, each R<SUP>1 </SUP>is group that will provide the therapeutically active compound upon hydrolysis of the polymer; each X is independently an ester linkage or an amide linkage; and R<SUP>2 </SUP>is a linking group.
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申请公布号 |
US2008234235(A1) |
申请公布日期 |
2008.09.25 |
申请号 |
US20080026925 |
申请日期 |
2008.02.06 |
申请人 |
UHRICH KATHRYN E;SCHMELTZER ROBERT C;ANASTASIOU THEODORE JAMES |
发明人 |
UHRICH KATHRYN E.;SCHMELTZER ROBERT C.;ANASTASIOU THEODORE JAMES |
分类号 |
A61K47/34;A61K47/48;C07C67/14;C07C69/353;C07C69/86;C07C231/12;C07C233/54;C08G63/00;C08G63/06;C08G63/44;C08G63/688;C08G67/04 |
主分类号 |
A61K47/34 |
代理机构 |
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主权项 |
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地址 |
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