| 摘要 |
Sirtuin-activating compounds (SACs) of enhanced solubility and bioavailability are described that contain at least one SAC with at least one solubility-enhancing organic material (solubility-enhancing organic material). Described methods to produce the bioenhanced products include dry blending and solvent spray drying. In one embodiment the solubility-enhancing organic material is polymeric. In accordance with certain embodiments of the invention, the method includes the steps of providing a mixture comprising at least one SAC, a solubility-enhancing polymer and a solvent and removing the solvent to form amorphous SAC. Products made by the invention's compositions and methods include pharmaceuticals, nutraceuticals, cosmetic, and personal care products for man and animal. |
