发明名称 Optically active cyclic alcohol compound and method for producing same
摘要 <p>The present invention relates to a method for preparing an optically active cyclic alcohol compound represented by general formula [I]: [wherein R represents a hydrogen atom or a protecting group for amino group, and * represents an asymmetric carbon atom.] which comprises a step of subjecting a cyclic ketone compound represented by general formula [II]: [wherein R has the same meaning as defined above.] to asymmetric reduction (A) in the presence of an optically active oxazaborolidine compound and a boron hydride compound, or (B) in the presence of an asymmetric transition metal complex obtained from a transition metal compound and an asymmetric ligand and a hydrogen donor, and relates to said compound.</p>
申请公布号 EP1944291(A1) 申请公布日期 2008.07.16
申请号 EP20060811186 申请日期 2006.10.04
申请人 MITSUBISHI TANABE PHARMA CORPORATION 发明人 OKAMOTO, MASAKI;SAKURAGI, AKIRA;MORI, YOSHIKAZU;KISHIDA, MUNEKI
分类号 C07D215/22;A61K31/4709;A61P11/06;A61P43/00;B01J31/02;B01J31/22;C07B53/00;C07B61/00;C07D215/233;C07D401/04 主分类号 C07D215/22
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