| 发明名称 |
Use of EDG receptor binding agents in cancer |
| 摘要 |
<p>Provided is a method for treating solid tumors, e.g tumor invasiveness, and particularly inhibiting or controlling deregulated angiogenesis, using a sphingosine-1-phosphate receptor agonist, optionally in combination with a chemotherapeutic agent. The invention also comprises a combination of a sphingosine-1-phosphate receptor agonist with a chemotherapeutic agent.</p> |
| 申请公布号 |
EP1944026(A2) |
申请公布日期 |
2008.07.16 |
| 申请号 |
EP20080152489 |
申请日期 |
2003.05.15 |
| 申请人 |
NOVARTIS AG;NOVARTIS PHARMA GMBH |
发明人 |
BAUMRUKER, THOMAS;BRINKMANN, VOLKER;LA MONTAGNE, KENNETH RICHARD;LASSOTA, PETER T;MECHTCHERIAKOVA, DIANA;WOOD, JEANETTE MARJORIE |
| 分类号 |
A61K31/135;A61K45/00;A61K31/137;A61K31/381;A61K31/661;A61P9/00;A61P35/00;A61P35/04;A61P43/00 |
主分类号 |
A61K31/135 |
| 代理机构 |
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