| 摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to an acid addition dopenzil salt [()-2-[(1-benzyl-4-piperidinyl)mathyl]-5,6-dimehoxy-1-indanone] of general formula (II), where X stands for a radical of fumaric acid prepared by reaction of dopenzil base and fumaric acid in ethanol or 2-propanol as a solvent, separation of dopenzil salt produced thereby and optionally washings with an organic solvent. The invention also concerns a pharmaceutical composition, the method of preparing the pharmaceutical compositions, application of acid addition dopenzil salt, and also the method for prevention or treatment of the diseases. ^ EFFECT: preparation of new acid addition dopenzil salt which is applicable for prevention or treatment of the diseases associated with acetylcholine lack in brain, Alzheimer's disease or senile psychosis. ^ 8 cl, 12 ex |
