摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, particularly to treatment of proliferative disease especially that one associated with a solid tumour. That is ensured by introduction of an effective amount of epothilone B of formula I wherein residual A represents O, R stands for hydrogen or methyl, and Z means O. The patient is exposed to ionising radiation additionally, simultaneously or consistently in any order. ^ EFFECT: choice of a specific epothilone derivative combined with radiation provides synergetic effect on suppression of tumour tissue. ^ 8 cl, 1 ex |