摘要 |
<p>FIELD: chemistry. ^ SUBSTANCE: invention relates to novel compounds of formula or to any isomer thereof, or mixture of isomers thereof, or pharmaceutically acceptable salt thereof, where R1 represents hydrogen or alkyl; R2 and R3 together form -(CH2)2-, and R2' and R3' represent hydrogen, m equals 1; n equals 1; X represents -O-; and Q represents chroman-2-on-7-yl, which is possibly substituted with one or more substitutes independently selected from a group consisting of halogen, trifluoromethyl, trifluoromethoxy, cyano, hydroxy, amino, nitro, alkoxy, cycloalkoxy, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl and alkynyl. The invention also relates to a pharmaceutical composition, as well as to use of chemical compound in any of paragraphs 1-4. ^ EFFECT: obtaining novel biologically active compounds having monoamine neuromediator reuptake inhibitory activity. ^ 8 cl, 10 ex, 1 tbl</p> |