摘要 |
PURPOSE: An apparatus and method for diagnosing Alzheimer diseases(AD) through measurement of vitamin D-binding protein is provided. CONSTITUTION: An apparatus for diagnosing Alzheimer contains an antibody which binds with vitamin D-binding protein, and a label which is conjugated with the antibody and generates proportional signal to total content of the antibody conjugated to vitamin D-binding protein. A bio sample is blood, serum, plasma, or platelet. The label is gold particle, color polystyrene micro particle, enzyme, fluorescent dye, conductive polymer, magnetic particle or peroxidase. A diagnosis strip(10) for Alzheimer disease comprises: a sample pad(12) receiving a liquid-phase sample; an adhesive pad(14) containing label-attached conjugate; a porous membrane pad(16) in which a binder is fixed; and an absorption pad(18) which finally receives liquid-phase sample.
|