摘要 |
According to the present invention, the following process for producing glutathione or ³-glutamylcysteine is provided. A process for producing glutathione or ³-glutamylcysteine by culturing in a medium a microorganism with a higher activity of one of the following proteins having an activity to transport intracellular glutathione to the outside of cells, and a higher activity of a protein involved in glutathione or ³-glutamylcysteine biosynthesis, compared with that of the parent strain, forming and accumulating glutathione or ³-glutamylcysteine in the medium, and recovering the glutathione or ³-glutamylcysteine from the culture.
[1] A protein having the amino acid sequence shown by any of SEQ ID NOs: 1 to 26
[2] A protein consisting of an amino acid sequence wherein one or more amino acids have been deleted, substituted or added in the amino acid sequence shown by any of SEQ ID NOs: 1 to 26, and having glutathione transporting activity
[3] A protein having 80% or more homology to the amino acid sequence shown by any of SEQ ID NOs: 1 to 26, and having glutathione transporting activity |