| 发明名称 |
DIFFERENTIAL EXPRESSION OF MICRORNAS IN NONFAILING VERSUS FAILING HUMAN HEARTS |
| 摘要 |
<p>The present invention discloses specific miRNAs as novel biomarkers and therapeutic targets in the treatment of heart failure. Methods of treating or preventing heart failure in a subject by administering mimics or inhibitors of these particular miRNAs are disclosed. A method of diagnosing or prognosing heart failure in a subject by determining the level of expression of one or more miRNAs is also described.</p> |
| 申请公布号 |
KR20100049079(A) |
申请公布日期 |
2010.05.11 |
| 申请号 |
KR20107003556 |
申请日期 |
2008.07.18 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF COLORADO |
发明人 |
PORT JONATHAN DAVID;SUCHAROV CARMEN;BRISTOW MICHAEL R. |
| 分类号 |
C12Q1/68;A61K31/7105;A61K48/00;C12N15/113 |
主分类号 |
C12Q1/68 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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