发明名称 Method of deprotection
摘要 The invention provides a method for the synthesis of an 18F-labelled product comprising deprotected of a protected 18F-labelled compound using a deprotection agent comprising a weak acid and wherein neutralisation and buffering of the deprotected product are carried out by the addition of a neutralisation agent. The deprotected product is buffered in a pH range suitable for subsequent autoclaving and formulation into an injectable radiopharmaceutical.
申请公布号 US7714115(B2) 申请公布日期 2010.05.11
申请号 US20050576625 申请日期 2005.09.23
申请人 GE HEALTHCARE LIMITED 发明人 GRIGG JULIAN;OSBORN NIGEL
分类号 C07H1/00;C07B59/00;C07D239/54;C07D239/553;C07D277/66;C07D401/06 主分类号 C07H1/00
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