| 摘要 |
FIELD: medicine, veterinary science. ^ SUBSTANCE: invention concerns veterinary medicine. vaccine contains inactivated antigen and adjuvant. The antigen contained in the vaccine is cell suspension of germ Pseudomonas aeruginosa pure culture. The culture is obtained by selecting target affected organs of fallen nutrias are taken from a local epizootic nidus, preparing suspension, inoculating in differentially diagnostic media, evolving pure culture of the germ and growing the culture in meat infusion broth until microbe cell concentration of 5-6 milliard per 1 cm3 is achieved. The vaccine also contains formalin and aluminium hydroxide in the following wt % ratio: cell suspension of germ Pseudomonas aeruginosa pure culture evolved from target affected organs of fallen nutria from a local epizootic nidus in meat infusion broth with titre of 5-6 milliard of microbal cells per 1 cm3- 83.0-85.5, formalin - 1.0-2.0, the remainder being aluminium hydroxide. ^ EFFECT: vaccine is safe, highly immunogenic and stable during storage. ^ 1 tbl, 5 ex |
