| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to new crystalline modifications of N--(2,4,6-triisopropylphenylsulphonyl)-3-hydroxyamidino-(L)-phenylalanine-4-ethoxycarbonyl piperazide and/or its salts. Such crystalline modifications have high stability particularly at low hygroscopicity compared to known amorphous forms of the compound. ^ EFFECT: invention relates to a method of obtaining such new crystalline modifications, to pharmaceutical compositions containing these new crystalline modifications and their use as an anti-tumour agent. ^ 26 cl, 7 tbl, 13 ex, 20 dwg |
