发明名称 Methods for synthesis of 3-amino-1-arylpropyl indoles
摘要 A method comprising: hydrogenating an indole propionamide compound of formula h with vitride, to form an aminopropyl indole compound of formula i wherein m, Ar, R1 and R2 are as defined herein. The compounds prepared by the method of the invention are useful as monoamine reuptake inhibitors useful for treatment of CNS indications.
申请公布号 US7598399(B2) 申请公布日期 2009.10.06
申请号 US20060605648 申请日期 2006.11.29
申请人 ROCHE PALO ALTO LLC 发明人 CONNOLLY TERRENCE JOSEPH;FARRELL ROBERT P.;HUMPHREYS ERIC ROY;LYNCH STEPHEN M.;SARMA KESHAB
分类号 C07D209/18 主分类号 C07D209/18
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