发明名称 Synthesis of antidiabetic rosiglitazone derivatives
摘要 A process of preparing rosiglitazone, or a pharmaceutically acceptable salt thereof, which process employs an intermediate metabisulphite complex of 4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzaldehyde, which metabisulphite complex is represented by following formula (III): where X represents an alkali metal. The present invention further provides rosiglitazone, or a pharmaceutically acceptable salt thereof, prepared by the above process.
申请公布号 US7598387(B2) 申请公布日期 2009.10.06
申请号 US20050568610 申请日期 2005.05.03
申请人 CIPLA LIMITED 发明人 RAO DHARMARAJ RAMACHANDRA;KANKAN RAJENDRA NARAYANRAO
分类号 C07D417/12;C07D213/74 主分类号 C07D417/12
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