发明名称 Method for producing a mixture of bacteriophages and its use in therapy of antibiotic-resistant staphylococci
摘要 <p>Method for preparing a mixture of bacteriophages, with which at least two different bacteriophage strains are separately propagated, comprises: (a) growing a Staphylococcusstrain with each strain of the bacteriophage, which can lyse staphylococci, in a preculture; (b) further propagating in a main culture; (c) subsequently purifying; and (d) subsequently mixing the various strains, where the used mixture of bacteriophage contains at least two different serotypes of bacteriophages that specifically lyse the bacteria of the species Staphylococcus. Independent claims are included for: (1) a phage mixture, obtained by the above method, comprising phages that have specific activity of at least 10 8>plaque forming units per mu g of protein; and (2) a medicament comprising the phage mixture. ACTIVITY : Antibacterial. MECHANISM OF ACTION : None given.</p>
申请公布号 EP2103308(A1) 申请公布日期 2009.09.23
申请号 EP20080005273 申请日期 2008.03.20
申请人 PHYTOLINE GMBH 发明人 MUELLER, ROBERT
分类号 A61K35/76;A61P31/04 主分类号 A61K35/76
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