发明名称 |
AMINO ACID SEQUENCES THAT MODULATE THE INTERACTION BETWEEN CELLS OF THE IMMUNE SYSTEM |
摘要 |
The present invention relates to amino acid sequences that block the interaction between (a target on) an antigen presenting cell (APC) and (a target on) a T-cell. More particularly, the present invention relates to amino acid sequences that are directed against (as defined herein) a target on an APC (also referred to herein as “APC target”) or a target on a T-cell (also referred to herein as “T-cell target”). The invention further relates to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. |
申请公布号 |
EP2102241(A2) |
申请公布日期 |
2009.09.23 |
申请号 |
EP20070856794 |
申请日期 |
2007.12.17 |
申请人 |
ABLYNX N.V. |
发明人 |
HERMANS, GUY;VERHEESEN, PETER;DOLK, EDWARD;HOOGENBOOM, HENDRICUS RENERUS JACOBUS MATTHEUS;SAUNDERS, MICHAEL JOHN SCOTT;DE HAARD, JOHANNES JOSEPH WILHELMUS;DE BRUIN, RENEE |
分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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