LIPOSOMAL GEL PHTHALOCYANINE PREPARATION FOR PHOTODYNAMIC THERAPY OF TUMORS AND ITS MANUFACTURING

摘要

The tumoral disease photodynamic therapy liposomal gel phthalocyanic medicine comprises e.g. hydrophobic clays or metal-free phthalocyanin mixed with transparent pharmaceutical gel in the 10:1 to 1:10 ratio. Also claimed is a process making the medicine. CLAIMED PROCESS - The process fluidizes lecithin (1-40 mg per mliter of liquid) to below 1000 nmeter at above 0 degrees C and 50-200 MPa. The lecithin can be extruded on the basis of a 50-100 nmeter filter and the gel is added to teh resulting suspension.